Influence of Age, BMI and Sex on Colorectal Cancer Risk

Hayder Oufi and Ruaa Alabd

Background and Objective: Colorectal cancer (CRC) risk is influenced by demographic factors such as age, Body Mass Index (BMI) and sex. This study aimed to investigate the association of these factors with CRC risk to inform targeted preventive interventions. Materials and Methods: In this case-control study, 70 CRC patients and 70 matched controls were recruited. Data were collected using structured questionnaires and medical records. Statistical analyses included t-tests, Chi-square tests and logistic regression to examine the relationships between age, BMI, sex and CRC risk. Statistical significance was set at p<0.05. Results: Higher age, male sex and elevated BMI were significantly associated with increased CRC risk. The mean age of CRC cases was 54.0±13.1 years versus 49.5±10.4 years in controls (p = 0.023). Mean BMI was higher in cases than controls (30.0±5.8 vs. 28.2±4.4, p = 0.045). The CRC incidence was greater in men than women (57.1% vs. 42.9%, p = 0.042). Conclusion: Age, BMI and male sex are important risk factors for CRC. These findings emphasize the need for prioritizing high-risk populations in CRC screening and prevention programs.

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